TRAN B. NGUYEN

Mr. Nguyen has served as Prothena’s Chief Strategy Officer since September 2021 and as Chief Financial Officer since 2013. He served as Chief Operating Officer from 2018 through September 2021. He has over 25 years of finance experience in the biotechnology, banking, and private equity industries. Prior to joining Prothena in 2013, Mr. Nguyen was the Chief Financial Officer at Somaxon Pharmaceuticals, Inc. from 2010 until its sale in 2013. He was the Chief Financial Officer at Metabasis Therapeutics, Inc. from 2009 until its sale in 2010. Mr. Nguyen previously served as a director of Rain Oncology Inc. from 2018 through its subsequent initial public offering in 2021 and sale in January 2024. Mr. Nguyen earned his BA in Economics and Psychology from Claremont McKenna College and his MBA from the Anderson School of Management at the University of California, Los Angeles.